The Feline Liver Has Low Tolerance To Toxins:
Many substances are especially toxic to cats because the liver has a low capacity to metabolize them. To repeat what Dr. Patrick Reeves stated, “Cats have a very low tolerance to toxins. If you give a Tylenol to a cat they are dead in 30 minutes. Not so for a dog.” As John K. Dunn states in his Textbook of Small Animal Medicine, “toxic side effects develop more easily in cats in cases of overdoses of toxins from plastic and other toxins, or reduced liver function.”
In the pictures below is a normal cats liver, where it is located in the cat and one that has cancer.
Mesenteric lymphosarcoma in a 13-year-old cachectic Domestic longhair cat which presented with acute inappetance and vomiting. The cat was subsequently euthanized and a post-mortem revealed a large central mesenteric mass. The kidneys were small, irregular-shaped and the liver shrunken and fibrotic. Courtesy Dr Jim Euclid